Board member Hugh Boyle poses for a portrait with what he believes is a section of a pillowcase that has Abraham Lincoln's blood and other material on it from Lincoln's assassination, at The Grand Army of the Republic Museum and Library in Philadelphia, Thursday, April 16, 2009.[Agencies]

The 16th president, he contends, had a rare genetic disorder — one that would likely have left him dead of cancer within a year had he not been assassinated. And his bid to prove his theory has posed an ethical and scientific dilemma for a small Philadelphia museum in the year that marks the 200th anniversary of Lincoln's birth.

Framed behind glass in the Grand Army of the Republic Civil War Museum and Library in northeast Philadelphia is a small piece of bloodstained pillowcase on which the head of the dying president rested after he was shot at Ford's Theater in Washington 144 years ago.

Sotos, a cardiologist and author, is hoping a DNA test of the strip will reveal whether Lincoln was afflicted with multiple endocrine neoplasia, type 2B. The disorder, which occurs in one in every 600,000 people, would explain Lincoln's unusual height, his relatively small and asymmetric head and bumps on his lips seen in photos, he said.

The disorder leads to thyroid or adrenal cancer, and Sotos cites Lincoln's weight loss in office and an appearance of ill health during his final months. He said a finding that Lincoln had the genetic disorder and probably cancer could shed light on his presidency.

"I'm not interested in how Lincoln might have died. I'm interested in how he might have lived," Sotos said.

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